Center for Comprehensive Lymphatic Care

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What Is Lymphedema?

Lymphedema is swelling of a body part, most often affecting the extremities, like the arms or legs. It can affect multiple areas of the body, such as the upper extremities, lower extremities, head, neck, chest and genitals. Lymphedema is caused by an abnormal accumulation of lymphatic fluid. Although it’s a progressive chronic condition, it can usually be controlled by medical attention and quality care.

Lymphedema Symptoms

Lymphedema symptoms can range from mild to severe:

  • Swelling
  • A feeling of heaviness or tightness
  • Hardening and thickening of the skin
  • Recurring infections
  • Restricted range of motion
Primary Lymphedema

Primary lymphedema cases occur without any obvious cause and may be present at birth, in adolescence or develop after age 35. Primary lymphedema is considered rare, occurs more in females and is most widely experienced in the legs.

Secondary Lymphedema

Secondary lymphedema, the most common form of the condition, is caused by injury, scarring or excision of the lymph nodes. It usually occurs because of previous radiation exposure, or from surgery on the lymph nodes. Occasionally, trauma or chronic infections of the lymphatic system can cause secondary lymphedema.

Lymphedema and Breast Cancer

How Does Lymphedema Occur With Breast Cancer?

The lymphatic collectors of the arm drain in most patients through the lymph nodes of the axilla or armpit. The lymphatic collectors of the breast also drain into the same lymph nodes. In breast cancer treatment, the axillary nodes are sampled to determine if the cancer has spread beyond the breast. This is called a sentinel node biopsy.

Sometimes, if there is cancer in the sentinel lymph node, most of the axillary nodes must be removed to prevent the cancer from coming back into the axilla (a procedure called an axillary lymph node dissection, or ALND).

The risk of developing lymphedema after a sentinel lymph node biopsy is small but can still occur. The risk of developing lymphedema after most axillary nodes are removed is much greater at about 20 to 30% of cases, especially if the axilla is treated with postoperative radiation therapy.

What are the Risk Factors for Developing Lymphedema with Breast Cancer?

  • Axillary lymph nodes dissection (ALND)
  • Axillary radiation
  • Developing a postoperative hematoma (blood clot in the wound)
  • Developing a postoperative infection
  • Having a BMI greater than 30
  • Having a total mastectomy
  • Receiving Taxane chemotherapy
  • Removing more than six nodes when performing a sentinel lymph node biopsy

Lymphedema Treatments

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Testing We Offer to Diagnose Lymphedema

  • Bioimpedance Spectroscopy
  • Indocyanine Green (ICG) Testing
  • MR Lymphangiogram
  • Nuclear Medicine Lymphoscintigraphy
  • Ultra-High Frequency Ultrasound
  • Venous Ultrasound

Lymphedema Surgery Options

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Your Lymphedema Experts

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Mikayla Alexis Ruane, PA-C

Mikayla Claudio, PA-C

Plastic Surgery

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Karyn Jarett

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Arian Dimsoy

LEARN Recognition

AdventHealth is recognized as a LEARN Comprehensive Network Center of Excellence in Lymphatic Disease.